HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Bromoprop-1-yn-1-yl)benzene → 2-Methoxy-2-[3-(3-phenylprop-2-ynyloxy)phenyl]-4-(2,5,5-trimethyl-1,3-dioxan-2-yl)but-1-yl methyl ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Bromoprop-1-yn-1-yl)benzene | HCID 10987157 | — |
| Reactant | 2-(3-Hydroxyphenyl)-2-methoxy-4-(2,5,5-trimethyl-1,3-dioxan-2-yl)but-1-yl methyl ether | HCID 19761560 | — |
| Product | 2-Methoxy-2-[3-(3-phenylprop-2-ynyloxy)phenyl]-4-(2,5,5-trimethyl-1,3-dioxan-2-yl)but-1-yl methyl ether | HCID 19761547 | 85% |
Reaction Steps
Using the procedure described in Example 12, 2-(3-hydroxyphenyl)-2-methoxy-4-(2,5,5-trimethyl-1,3-dioxan-2-yl)but-1-yl methyl ether was reacted with 3-phenylprop-2-ynyl bromide to give 2-methoxy-2-[3-(3-phenylprop-2-ynyloxy)phenyl]-4-(2,5,5-trimethyl-1,3-dioxan-2-yl)but-1-yl methyl ether in 85% yield, as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05132328 |
| Source dataset | uspto-grants-1992_07 |
| ORD ID | ord-a235f881b4e24bb5966e1e0739acd897 |
| Source note | uspto-grants-1992_07 |