Methyl iodide → HCID 271998, compound

HRID 654758Notes

Reaction equation

HRID 654758 reaction equation
CS[CH2:3][C:4]1[O:5][C:6]2[C:11]([C:12](=[O:14])[CH:13]=1)=[CH:10][CH:9]=[CH:8][CH:7]=2.C[I:16]>ClCCl>[I:16][CH2:3][C:4]1[O:5][C:6]2[C:11]([C:12](=[O:14])[CH:13]=1)=[CH:10][CH:9]=[CH:8][CH:7]=2

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 141005932-[(Methylsulfanyl)methyl]-4H-1-benzopyran-4-one

Product 1

HCID 271998HCID 271998, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

8 g of 2-methylthiomethyl-4-oxo-4H-chromene, 200 ml of methyl iodide and 26 ml of dichloromethane are brought to reflux with stirring for 4 days. The precipitate is filtered off, the excess solvents and reagents are evaporated off, the residue is taken up with ethyl ether and the organic phase is washed with sodium thiosulfate solution, dried and evaporated.

Workup

  1. temperatureto reflux
  2. filtrationThe precipitate is filtered off
  3. customthe excess solvents and reagents are evaporated off
  4. washthe organic phase is washed with sodium thiosulfate solution
  5. customdried
  6. customevaporated

Sources & evidence

ORD record
ord-c1e1cedb3d38419a9113e8e0273f4061
Source dataset
uspto-grants-1992_07
Patent number
US05134147

Reaction notes

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