3-(Piperidin-4-yl)benzo[d]isoxazole → 3-[1-(Benzocyclobuten-1-ylmethyl)-4-piperidyl]-1,2-benzisoxazole

HRID 654766Notes

Reaction equation

HRID 654766 reaction equation
[C:1]1([C:9](O)=O)[C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[CH:2]=1.[NH:12]1[CH2:17][CH2:16][CH:15]([C:18]2[C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=3[O:20][N:19]=2)[CH2:14][CH2:13]1>>[C:1]1([CH2:9][N:12]2[CH2:13][CH2:14][CH:15]([C:18]3[C:22]4[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=4[O:20][N:19]=3)[CH2:16][CH2:17]2)[C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[CH:2]=1

Participants

3

Reactant 2

HCID 130764363-(Piperidin-4-yl)benzo[d]isoxazoleHCID 178524025HCID 178524025, compound

Product 1

HCID 198864023-[1-(Benzocyclobuten-1-ylmethyl)-4-piperidyl]-1,2-benzisoxazole

Procedure

3-[1-(Benzocyclobuten-1-ylmethyl)-4-piperidyl]-1,2-benzisoxazole was prepared from benzocyclobutene-1-carboxylic acid and 3-piperid-4-yl-1,2-benzisoxazole according to the process described in Example 19, stages A and B.

Sources & evidence

ORD record
ord-5e7f8b52a911444ca23fa7f5d0c223ec
Source dataset
uspto-grants-1992_07
Patent number
US05134147

Reaction notes

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