HCID 19885941, compound → HCID 19885887, compound

Participants

Reaction Steps

To a stirred solution of (E)-ethyl 9-phenylnon-6-enoate (1.45 g, 5.53 mmol) in methylene chloride (35 ml) under argon at 0° was added diisobutylaluminum hydride (15.0 ml of a 1.0M solution). This mixture was warmed to room temperature and quenched with 10% aqueous hydrochloric acid. The organic portion was washed with saturated sodium bicarbonate solution, water, saturated sodium chloride solution, dried over magnesium sulfate, filtered and concentrated to give a colorless oil. Purification by flash chromatography (silica, 20% ethyl acetate/hexane) gave the desired alcohol.

Provenance & Evidence