反应详情

A solution of 5-(2-pyridyl)-4-pentyn-1-ol (1 g, 6.2 mmol) in diethyl ether (15 ml) was hydrogenated over 10% palladium on carbon at room temperature for 16 h. The mixture was filtered through celite and the filtrate on evaporation gave an oil, which was flash chromatographed on silica using 80% ethyl acetate/chloroform. Fractions with Rf of about 0.06 on evaporation gave the title alcohol as a yellow oil.

1. filtrationThe mixture was filtered through celite
2. customthe filtrate on evaporation
3. customgave an oil, which
4. customchromatographed on silica using 80% ethyl acetate/chloroform
5. customFractions with Rf of about 0.06 on evaporation