Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Benzaldehyde, 3,4-bis[(4-methoxyphenyl)methoxy]- | HCID 10619649 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67742855 | HCID 67742855 | 85% |
Reaction Steps
To a solution of 3,4-dihydroxy-ω-chloroacetophenone (1) (1.65 g: 8.84 mMol.) in dichloromethane (17 ml) keeping at 0° C. are added pyridine (1.64 ml: 2.3 Eq.) and acetyl chloride (1.45 ml: 2.3 Eq.), and the mixture is stirred at 0° C. for 30 minutes. The reaction mixture is diluted with ethyl acetate, washed with water, dried, and concentrated under reduced pressure to give 3,4-diacetoxy-ω-chloroacetophenone (2) (2.03 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05134138 |
|---|
| Source dataset | uspto-grants-1992_07 |
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| ORD ID | ord-b6b56693b0704fa4aff921c7d927107a |
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| Source note | uspto-grants-1992_07 |
|---|
