Ammonium formate → HCID 67541672, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 1-{(R)-1-[9-[(2R,3R,4S,5R)-5-(2-Benzyl-2H-tetrazol-5-yl)-3,4-dihydroxy-tetrahydro-furan-2-yl]-6-(2,2-diphenyl-ethylamino)-9H-purin-2-yl]-pyrrolidin-3-yl}-3-pyridin-3-yl-urea in EtOH under an inert atmosphere of argon is treated with 10% palladium on carbon followed by ammonium formate. The reaction mixture is heated to 50° C. for 4 hours and then filtered through Celite®. The filtrate is concentrated in vacuo to afford the title compound.

Provenance & Evidence