化工社化工社 化学情報印刷レポート · 研究参考用
(1S,4S)-4-(3-pyridyl)-2-cyclopenten-1-ol → (1R,3R)-3-(3-pyridyl)cyclopentanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (1S,4S)-4-(3-pyridyl)-2-cyclopenten-1-ol | HCID 59486121 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (1R,3R)-3-(3-pyridyl)cyclopentanol | HCID 59486143 | 97% |
反応手順
A mixture of (1S,4S)-4-(3-pyridyl)-2-cyclopenten-1-ol (1.86 g, 11.5 mmol) and 10% Pd/C (186 mg) in EtOH (35 mL) was stirred under hydrogen atmosphere for 3 h. The catalyst was removed by filtration over Celite and the filtrate was concentrated in vacuo. (1R,3R)-3-(3-pyridyl)cyclopentanol (1.82 g, 97%) was yield as yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08071591B2 |
| 出典データセット | uspto-grants-2011_12 |
| ORD ID | ord-f2d094fcfd834f89a25ee48b8793f655 |
| 出典メモ | uspto-grants-2011_12 |