Methyl chloroformate → HCID 67530210, compound

HRID 655200Notes

Reaction equation

HRID 655200 reaction equation
[C:1]([N:5]([CH3:32])[C:6]([C:8]1[N:12]2[CH2:13][CH2:14][C:15]3[C:20]([C:11]2=[C:10]([C:27]2[S:28][CH:29]=[CH:30][CH:31]=2)[N:9]=1)=[CH:19][C:18]([O:21][CH2:22][CH2:23][NH2:24])=[C:17]([O:25][CH3:26])[CH:16]=3)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl[C:34]([O:36][CH3:37])=[O:35]>>[CH3:37][O:36][C:34](=[O:35])[NH:24][CH2:23][CH2:22][O:21][C:18]1[CH:19]=[C:20]2[C:15]([CH2:14][CH2:13][N:12]3[C:8]([C:6](=[O:7])[N:5]([C:1]([CH3:3])([CH3:4])[CH3:2])[CH3:32])=[N:9][C:10]([C:27]4[S:28][CH:29]=[CH:30][CH:31]=4)=[C:11]32)=[CH:16][C:17]=1[O:25][CH3:26]

Participants

3

Procedure

Coupling of the product of example 31 (50 mg) with methyl chloroformate (11 μl) was performed according to the method described in example 32.

Sources & evidence

ORD record
ord-5cb5cc0b31bf40518664f9b1c3ae2071
Source dataset
uspto-grants-2011_12
Patent number
US08071587B2

Reaction notes

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