Methanol → HCID 59320376, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of [3-(1-methyl-1H-pyrazole-4-yl)-quinolin-6-yl]-acetic acid (2.4 g, 8.6 mmols) and methanol (12 mL) at 0° C. was added thionyl chloride (2 eq., 17.2 mmols) in a dropwise fashion. The reaction mixture was then heated to 60° C. for one hour. The solvent was removed under vacuum and used in the next step without further purification. MS m/z: 282 (M+H+).

Provenance & Evidence