反应详情

A mixture of 6-(6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-3-vinyl-quinoline (20 mg, 0.0664 mmol) and palladium on carbon (10% wt, 20 mg) in ethanol (1.5 mL) under a hydrogen atmosphere was stirred vigorously at ambient temperature for 4 hours. The mixture was then filtered through a pad of celite and the filtrate concentrated to provide the title compound (15 mg, 75% yield). Analytical data presented in Table 1.

1. filtrationThe mixture was then filtered through a pad of celite
2. concentrationthe filtrate concentrated