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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 655343Generated: October 25, 2026

5-Methyloxazolo[4,5-b]pyridin-2(3H)-one → 5-methyl-3-[3-(5-methylpyridin-2-yl)benzyl]-3H-oxazolo[4,5-b]-pyridin-2-one

https://huagongshe.com/reaction/655343

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methyloxazolo[4,5-b]pyridin-2(3H)-oneHCID 10012075—
Reactant(3-(5-Methylpyridin-2-yl)phenyl)methanolHCID 56604357—
Product5-methyl-3-[3-(5-methylpyridin-2-yl)benzyl]-3H-oxazolo[4,5-b]-pyridin-2-oneHCID 59564723—

Reaction Steps

Reaction of [3-(5-methylpyridin-2-yl)phenyl]methanol with 5-methyl-3H-oxazolo[4,5-b]pyridin-2-one under Mitsunobu conditions gives the desired 5-methyl-3-[3-(5-methylpyridin-2-yl)benzyl]-3H-oxazolo[4,5-b]-pyridin-2-one, ESI 332 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071593B2
Source datasetuspto-grants-2011_12
ORD IDord-322d0eb93d354295b175707aa24d076f
Source noteuspto-grants-2011_12