Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Benzoyl-2-chloropyridine → 3-Pyridinemethanol, 2-chloro-alpha-phenyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Benzoyl-2-chloropyridine | HCID 824619 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 3-Pyridinemethanol, 2-chloro-alpha-phenyl- | HCID 3061980 | 42.1% |
반응 단계
2.4 g lithium aluminium hydride is added very slowly to 10.6 g 3-benzoyl-2-chloropyridine in 100 ml anhydrous pyridine. After stirring for 2 hrs. at room temperature, the solvent is distilled in vacuo, the residue is added to 5% aqueous HCl and extracted with ether. Working as usual there is obtained 4.5 g of a product, identical with that obtained as in (a).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04614833 |
| 출처 데이터셋 | uspto-grants-1986_09 |
| ORD ID | ord-f956151d754e4214abeff007d693b905 |
| 출처 메모 | uspto-grants-1986_09 |