2-(Chloromethyl)-5-methylpyridine → HCID 59354843, compound

HRID 655469Notes

Reaction equation

HRID 655469 reaction equation
[CH3:1][C:2]1([CH3:27])[C:6]([CH3:8])([CH3:7])[O:5][B:4]([C:9]2[CH:26]=[CH:25][C:12]([O:13][CH2:14][C:15]3[CH:24]=[CH:23][C:22]4[C:17](=CC=C[CH:21]=4)[N:16]=3)=[CH:11][CH:10]=2)[O:3]1.ClCC1C=CC(C)=CN=1>N1C=CC=CC=1>[CH3:21][C:22]1[CH:23]=[CH:24][C:15]([CH2:14][O:13][C:12]2[CH:11]=[CH:10][C:9]([B:4]3[O:5][C:6]([CH3:8])([CH3:7])[C:2]([CH3:27])([CH3:1])[O:3]3)=[CH:26][CH:25]=2)=[N:16][CH:17]=1

Participants

4

Reactant 2

HCID 5880562-(Chloromethyl)-5-methylpyridineHCID 583680032-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)methyl)quinoline

Product 1

HCID 59354843HCID 59354843, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

5-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)methyl)pyridine may be prepared in a manner analogous to 2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)methyl)quinoline using 2-(chloromethyl)-5-methylpyridine instead of 2-(chloromethyl)quinoline.

Sources & evidence

ORD record
ord-26cc71d630ea4eb981c88bc89e47e9fa
Source dataset
uspto-grants-2011_12
Patent number
US08071595B2

Reaction notes

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