HCID 67080074, compound → HCID 67079874, compound

Participants

Reaction Steps

A solution of (S)-4-[3-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-propyl]-2-methyl-3-oxo-piperazine-1-carboxylic acid benzyl ester (950 mg, 2.29 mmol) in methanol (25 ml) was stirred for 5 h under a hydrogen atmosphere (1 bar) in the presence of palladium (10% on activated charcoal, 243 mg), then insoluble material was removed by filtration and the filtrate evaporated to produce the title compound (642 mg, 100%). Orange oil, MS (ISP)=282.3 (M+H)+.

Provenance & Evidence