tert-Butyl acrylate → HCID 67079821, compound

HRID 655567Notes

Reaction equation

HRID 655567 reaction equation
[NH2:1][C@@H:2]([CH2:4][OH:5])[CH3:3].[C:6]([O:10][C:11](=[O:14])[CH:12]=[CH2:13])([CH3:9])([CH3:8])[CH3:7].[CH2:15]([O:22][C:23](ON1C(=O)CCC1=O)=[O:24])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:6]([O:10][C:11](=[O:14])[CH2:12][CH2:13][N:1]([C:23]([O:22][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:24])[C@H:2]([CH3:3])[CH2:4][OH:5])([CH3:9])([CH3:8])[CH3:7]

Participants

4

Reactant 3

HCID 15458tert-Butyl acrylateHCID 80308(R)-(-)-2-Amino-1-propanolHCID 83172Benzyl succinimido carbonate

Product 1

HCID 67079821HCID 67079821, compound

Procedure

In analogy to the procedure described in intermediate 8A, D-alaninol, tert-butyl-acrylate and N-(benzyloxycarbonyloxy)succinimide gave the title compound in quantitative yield as a light yellow oil. MS: 338.1 (MH+).

Sources & evidence

ORD record
ord-750827f3de1b49a9ad0ea298c5c52edd
Source dataset
uspto-grants-2011_12
Patent number
US08071586B2

Reaction notes

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