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HRID655570

反应详情

EQUATION

反应方程式

HRID 655570 的结构方程式

REACTANTS

反应物

2
结构：O=C=Nc1cccc(Cl)c1
HCID17968

m-Chlorophenyl isocyanate

C7H4ClNO

结构：C[C@@H]1CN(CCCN2CCC3(CC3)[C@H](O)C2)C(=O)CCN1.Cl.Cl
HCID67080697

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H]1CN(CCCN2CCC3(CC3)[C@H](O)C2)C(=O)CCN1C(=O)Nc1cccc(Cl)c1
HCID59149894

未命名化合物

收率 73%

PROCEDURE

实验过程

In analogy to the procedure described in example 58F, (R)-4-[3-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-propyl]-2-methyl-[1,4]diazepan-5-one dihydrochloride (example 58E) and 3-chlorophenyl isocyanate (without addition of 0.1 eq. of 3-chlorophenyl isocyanate) gave 0.081 g (73%) of the title compound as white foam. MS: 449.3 (MH+, 1Cl).