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HRID655571

反应详情

EQUATION

反应方程式

HRID 655571 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(N=C=O)cc1C
HCID4389663

4-isocyanato-1,2-dimethylbenzene

C9H9NO

结构：C[C@@H]1CN(CCCN2CCC3(CC3)[C@H](O)C2)C(=O)CCN1.Cl.Cl
HCID67080697

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(NC(=O)N2CCC(=O)N(CCCN3CCC4(CC4)[C@H](O)C3)C[C@H]2C)cc1C
HCID59149950

未命名化合物

收率 32%

PROCEDURE

实验过程

In analogy to the procedure described in example 58F, (R)-4-[3-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-propyl]-2-methyl-[1,4]diazepan-5-one dihydrochloride (example 58E) and 3,4-dimethylphenyl isocyanate (without addition of 0.1 eq. of 3,4-dimethylphenyl isocyanate) gave 0.035 g (32%) of the title compound as white foam. MS: 443.3 (MH+).