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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 655579Generated: October 30, 2026

Benzene, 1-chloro-3-isocyanato- → HCID 67080644, compound

https://huagongshe.com/reaction/655579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-chloro-3-isocyanato-HCID 17968—
ReactantHCID 67080781HCID 67080781—
ProductHCID 67080644HCID 6708064458%

Reaction Steps

In analogy to the procedure described for intermediate 58F, (R)-4-[(S)-3-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-1-methoxymethyl-propyl]-2-methyl-[1,4]diazepan-5-one dihydrochloride and 3-chlorophenyl isocyanate gave the title compound in 58% yield as yellow oil. MS: 493.4 (MH+, 1Cl).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071586B2
Source datasetuspto-grants-2011_12
ORD IDord-ecd81a8b35cf4482bd8aafd56daa3491
Source noteuspto-grants-2011_12