Dichloromethane → HCID 69243008, compound

Participants

Reaction Steps

To a solution of 4-bromobenzoyl chloride (0.600 g, 2.700 mmol) in dichloromethane (20 mL) was added 2-cyclopropylethylamine (0.270 g, 3.28 mmol) at 0° C. The mixture was stirred at ambient temperature for 12 hours, then washed sequentially with diluted HCl solution and NaHCO3. The organic phase was separated, dried and concentrated. The residue was purified by column chromatography and recrystallization from ethyl acetate and hexane to afford 4-chloro-N-(2-cyclopropylethyl)benzamide.

Provenance & Evidence