HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → 2-Amino-5-(dimethylamino)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | 5-(Dimethylamino)-2-nitrobenzoic acid | HCID 12715793 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-5-(dimethylamino)benzoic acid | HCID 12715794 | 61.1% |
Reaction Steps
The mixture of 2.1 g of 2-nitro-5-dimethylaminobenzoic acid, 7 mL of cyclohexene and 1.5 g of Pd/C (10%) is heated under reflux conditions in 60 mL of ethanol for 6 hours. The hot reaction mixture is filtered through celite filter. The filtrate is evaporated to obtain 1.1 g of the title compound. M.p.: 232° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071601B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-af4d6af51eeb4234924ded33931cec19 |
| Source note | uspto-grants-2011_12 |