HuagongsheHuagongshe Chemistry Print Report · For research reference only
Furfurylamine → 2-Amino-3-cyano-4-[2-furylmethylamino]-6-dimethylaminoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Furfurylamine | HCID 3438 | — |
| Reactant | 2-Amino-3-cyano-4-chloro-6-dimethylaminoquinoline | HCID 66850378 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Amino-3-cyano-4-[2-furylmethylamino]-6-dimethylaminoquinoline | HCID 66850344 | — |
Reaction Steps
3 g of 2-amino-3-cyano-4-chloro-6-dimethylaminoquinoline and 6 mL of furfurylamine are stirred at 125° C. for 3 hours. The reaction mixture is poured onto 30 mL of water. The precipitated material is filtered off, washed with 20 mL of water. After drying 2.05 g of the title compound is obtained, m.p.: 235° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071601B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-1001ab9e3f934574b9876d917ef16455 |
| Source note | uspto-grants-2011_12 |