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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 655882Generated: October 27, 2026

Selenium Dioxide → 5-Bromo-6-methoxy-2-quinolinecarbaldehyde

https://huagongshe.com/reaction/655882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSelenium DioxideHCID 24007—
Reactant5-Bromo-6-methoxy-2-methylquinolineHCID 11425256—
Product5-Bromo-6-methoxy-2-quinolinecarbaldehydeHCID 5751695175%

Reaction Steps

The title compound was prepared from 5-bromo-6-methoxy-2-methylquinoline (6b) and selenium dioxide using methods as described in the literature for similar compounds (Mathes et al., 1957) in 75% yield. 1H NMR (DMSO-d6, HMDSO), δ: 4.07 (3H, s); 7.92 (1H, d, J=9.0 Hz); 8.03 (1H, d, J=9.2 Hz); 8.29 (1H, d, J=9.2 Hz); 8.58 (1H, d, J=9.0 Hz), 10.09 (3H, s).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071620B2
Source datasetuspto-grants-2011_12
ORD IDord-f05654ec13ed4363be9af5af93ef0de8
Source noteuspto-grants-2011_12