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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 655884Generated: October 25, 2026

Benzyl Bromide → 8-(Benzyloxy)quinoline-2-carbaldehyde

https://huagongshe.com/reaction/655884

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant2-Methyl-8-hydroxyquinolineHCID 13224—
ReactantSelenium DioxideHCID 24007—
Product8-(Benzyloxy)quinoline-2-carbaldehydeHCID 153476935%

Reaction Steps

The title compound was prepared from 8-hydroxy-2-methylquinoline (6d), benzyl bromide, and selenium dioxide using methods as described in the literature for similar compounds (Buchi et al., 1956) in 35% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071620B2
Source datasetuspto-grants-2011_12
ORD IDord-b4fe30d4def747eca6f38b9193a0fa2b
Source noteuspto-grants-2011_12