HRID655904

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)c1cc(-c2c(OC)cc(OC)cc2OC)cc(CN2CCN(Cc3cc(-c4c(OC)cc(OC)cc4OC)cc(C(=O)OCC)n3)CCN(Cc3cc(-c4c(OC)cc(OC)cc4OC)cc(C(=O)OCC)n3)CC2)n1

HCID11194088

未命名化合物

HCID11572508

未命名化合物

PRODUCTS

生成物

结构：COc1cc(OC)c(-c2cc(CN3CCN(Cc4cc(-c5c(OC)cc(OC)cc5OC)cc(C(=O)O)n4)CCN(Cc4cc(-c5c(OC)cc(OC)cc5OC)cc(C(=O)O)n4)CC3)nc(C(=O)O)c2)c(OC)c1.[Tb+3]

HCID86600223

未命名化合物

PROCEDURE

实验过程

Deprotection of compound 21 followed by treatment with terbium chloride as described in Example 20 yielded the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7a90acc0d373494596238c6aa682ff2d
来源数据集: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08071626B2
来源说明: uspto-grants-2011_12

反应 SMILES

C([O:3][C:4]([C:6]1[N:11]=[C:10]([CH2:12][N:13]2[CH2:21][CH2:20][N:19]([CH2:22][C:23]3[CH:28]=[C:27]([C:29]4[C:34]([O:35][CH3:36])=[CH:33][C:32]([O:37][CH3:38])=[CH:31][C:30]=4[O:39][CH3:40])[CH:26]=[C:25]([C:41]([O:43]CC)=[O:42])[N:24]=3)[CH2:18][CH2:17][N:16]([CH2:46][C:47]3[N:52]=[C:51]([C:53]([O:55]CC)=[O:54])[CH:50]=[C:49]([C:58]4[C:63]([O:64][CH3:65])=[CH:62][C:61]([O:66][CH3:67])=[CH:60][C:59]=4[O:68][CH3:69])[CH:48]=3)[CH2:15][CH2:14]2)[CH:9]=[C:8]([C:70]2[C:75]([O:76][CH3:77])=[CH:74][C:73]([O:78][CH3:79])=[CH:72][C:71]=2[O:80][CH3:81])[CH:7]=1)=[O:5])C.[Cl-].[Tb+3:83].[Cl-].[Cl-]>>[Tb+3:83].[C:41]([C:25]1[N:24]=[C:23]([CH2:22][N:19]2[CH2:18][CH2:17][N:16]([CH2:46][C:47]3[CH:48]=[C:49]([C:58]4[C:63]([O:64][CH3:65])=[CH:62][C:61]([O:66][CH3:67])=[CH:60][C:59]=4[O:68][CH3:69])[CH:50]=[C:51]([C:53]([OH:55])=[O:54])[N:52]=3)[CH2:15][CH2:14][N:13]([CH2:12][C:10]3[N:11]=[C:6]([C:4]([OH:5])=[O:3])[CH:7]=[C:8]([C:70]4[C:71]([O:80][CH3:81])=[CH:72][C:73]([O:78][CH3:79])=[CH:74][C:75]=4[O:76][CH3:77])[CH:9]=3)[CH2:21][CH2:20]2)[CH:28]=[C:27]([C:29]2[C:30]([O:39][CH3:40])=[CH:31][C:32]([O:37][CH3:38])=[CH:33][C:34]=2[O:35][CH3:36])[CH:26]=1)([OH:43])=[O:42]