Triacetoxyperiodinane → HCID 86638995, compound

Participants

Reaction Steps

Thiobenzoic acid S-((1R,2R,5S)-5-tert-butoxycarbonylamino-2-hydroxy-cyclohexyl) ester+(1S,2S,5R) diastereomer (8.7 g, 24.8 mmol) from Example 34 Step A was treated with 1,1-dihydro-1,1,1-triacetoxy-1,2-benziodoxol-3(1H)-one (11.02 g, 26 mmol) according to the method of Example 34 Step B. After work up and chromatography (silica, toluene/ethyl acetate=6/1) of the mixture the title compound (toluene/ethyl acetate=3/1, Rf=0.43, 7.15 g, 83% yield) was obtained as a white solid.

Provenance & Evidence