2-Amino-5-bromopyrimidine → HCID 68653043, compound

HRID 656238Notes

Reaction equation

HRID 656238 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][C:5]([NH2:8])=[N:6][CH:7]=1.Cl[CH:10]([CH2:14][CH2:15][CH2:16][O:17][CH3:18])[C:11](=O)[CH3:12]>>[Br:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([C:10]([CH2:14][CH2:15][CH2:16][O:17][CH3:18])=[C:11]([CH3:12])[N:8]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 2313102-Amino-5-bromopyrimidineHCID 86639839HCID 86639839, compound

Product 1

HCID 68653043HCID 68653043, compound

Procedure

0.85 mmol of 5-bromopyrimidin-2-ylamine [7752-82-1] and 1.7 mmol of 3-chloro-6-methoxyhexan-2-one are reacted in analogy to building block 35. The title compound is identified by means of the Rf.

Sources & evidence

ORD record
ord-222e1af1e07a489a8dfce6a71cc8e413
Source dataset
uspto-grants-2011_12
Patent number
US08071651B2

Reaction notes

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