HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → 1,5-Anhydro-2,3-dideoxy-2-(methoxycarbonyl)-erythropentitol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | HCID 68653086 | HCID 68653086 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1,5-Anhydro-2,3-dideoxy-2-(methoxycarbonyl)-erythropentitol | HCID 69124467 | — |
Reaction Conditions
| Temperature | 0 °C |
|---|
Reaction Steps
A solution of diazomethane in diethyl ether (approx. 0.4 M) is added in excess to a solution of 23 mmol of (cis)-5-hydroxytetrahydropyran-3-carboxylic acid in 300 ml of methanol at 0° C. The mixture is stirred at 0° C. for 2 hours and then quenched with magnesium sulphate, filtered and evaporated. The crude title compound is identified by means of the Rf.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071651B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-1e55ef36458c48b4ac63172872a7f8d4 |
| Source note | uspto-grants-2011_12 |