HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(1-methyl-1H-pyrrol-2-yl)methanamine → 1-(4-t-butylbenzyl)-3-(1-methyl-1H-pyrrol-2-yl)methylthiourea
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (1-methyl-1H-pyrrol-2-yl)methanamine | HCID 2776207 | — |
| Edukt | 1-Tert-butyl-4-(isothiocyanatomethyl)benzene | HCID 14801041 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | 1-(4-t-butylbenzyl)-3-(1-methyl-1H-pyrrol-2-yl)methylthiourea | HCID 59088065 | 75,9% |
Reaktionsschritte
(1-methyl-1H-pyrrol-2-yl)methylamine (65 mg) and 4-t-butylbenzylisothiocyanate (120 mg) were dissolved in ethyl acetate (30 ml) and the solution was stirred for 12 hours. After the completion of the reaction, the resulting mixture was purified by column-chromatography (ethyl acetate/hexane=1/3) to yield the compound 17-2 (140 mg, 75%)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08071650B2 |
| Quelldatensatz | uspto-grants-2011_12 |
| ORD ID | ord-ad0f65674d824e39a75806ea578f636e |
| Quellennotiz | uspto-grants-2011_12 |