HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86086990, compound → HCID 66743353, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86086990 | HCID 86086990 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66743353 | HCID 66743353 | 112.5% |
Reaction Steps
A mixture of 4′-azido-3H-spiro[2-benzofuran-1,1′-cyclohexan]-3-one (90 mg, 0.36 mmol) in methanol (5 mL) with 10% palladium on charcoal (30 mg) was stirred under hydrogen atmosphere (balloon) for 1 hour. After filtration, the solution was concentrated to yield 88 mg of 4′-amino-3H-spiro[2-benzofuran-1,1′-cyclohexan]-3-one (yield: 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071624B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-e88e75be7313404a9474ece26ac58fdd |
| Source note | uspto-grants-2011_12 |