(+/-)-5'-Amino-6'-nitro-3-methyl-spiro[imidazolidine-4,2'-indane]-2,5-dione → 5',6'-Diamino-3-methyl-spiro[imidazolidine-4,2'-indane]2,5-dione

Participants

Reaction Steps

To a solution of (±)-5′-amino-6′-nitro-spiro[imidazolidine-4,2′-indane]-2,5-dione from Step A (15 mg, 0.054 mmol) in MeOH (5 mL) was added 10% Pd/C (5 mg) and the reaction mixture was stirred vigorously under hydrogen (ca. 1 atm). After 2 h, the catalyst was filtered off and the filtrate was concentrated in vacuo to yield the title compound. MS: m/z=247 (M+1).

Provenance & Evidence