Ammonium Chloride → HCID 66915443, compound

Participants

Reaction Steps

A solution of 1 mmol of 4-(1-benzyl-1H-imidazol-4-yl)-7-methoxychromen-2-one in 5 ml of tetrahydrofuran is added to a solution of 3 mmol of 3-(phenylmethoxy)propylmagnesium bromide [183312-54-1] in 5 ml of tetrahydrofuran. The mixture is subsequently stirred for 1 hour and then poured into saturated aqueous ammonium chloride solution. It is extracted with diethyl ether (3×). The combined organic phases are dried over sodium sulphate and evaporated. From the residue the title compound is identified by means of flash chromatography (SiO2 60F) on the basis of the Rf value.

Provenance & Evidence