8-Methylsulfonyl-12-hydroxy-13,13-dimethyl-10-heptadecynoic acid → 8-Methylsulfonyl-12-hydroxy-13,13-dimethylheptadecanoic acid

HRID 65649Notes

Reaction equation

HRID 65649 reaction equation
CS(C(CC#C[C@@H](O)CCCCC)CCCCCCC(O)=O)(=O)=O.[CH3:25][S:26]([CH:29]([CH2:39][C:40]#[C:41][CH:42]([OH:50])[C:43]([CH3:49])([CH3:48])[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][C:36]([OH:38])=[O:37])(=[O:28])=[O:27]>>[CH3:25][S:26]([CH:29]([CH2:39][CH2:40][CH2:41][CH:42]([OH:50])[C:43]([CH3:49])([CH3:48])[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][C:36]([OH:38])=[O:37])(=[O:27])=[O:28]

Participants

3

Reactant 2

HCID 213176218-Methylsulfonyl-12-hydroxy-13,13-dimethyl-10-heptadecynoic acidHCID 227969758-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid

Product 1

HCID 213176228-Methylsulfonyl-12-hydroxy-13,13-dimethylheptadecanoic acid

Procedure

The synthesis of this compound is carried out by hydrogenation exactly as described in Example 15 except that 8-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid is replaced by an equivalent quantity of 8-methylsulfonyl-12-hydroxy-13,13-dimethyl-10-heptadecynoic acid.

Workup

  1. customThe synthesis of this compound

Sources & evidence

ORD record
ord-49fcb198646745c08f11fb90cf144eaa
Source dataset
uspto-grants-1978_12
Patent number
US04128564

Reaction notes

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