HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → N-(1-benzylazepan-4-yl)-1H-indazol-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | N-Boc-hexahydro-1H-azepin-4-one | HCID 1512679 | — |
| Reactant | 2,2-Dimethyl-1-(5-(piperidin-3-ylamino)-1H-indazol-1-yl)propan-1-one | HCID 59799768 | — |
| Product | N-(1-benzylazepan-4-yl)-1H-indazol-5-amine | HCID 44595809 | — |
Reaction Steps
The title compound was prepared by reaction of 2,2-dimethyl-1-(5-(piperidin-3-ylamino)-1H-indazol-1-yl)propan-1-one with tert-butyl 4-oxoazepane-1-carboxylate using the method of Example 3, deprotection using the method of Example 4, reaction with benzaldehyde following the method of Example 8, and final deprotection using the method of Example 9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071779B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-1187ad393f0647ca8479f456d6070c9d |
| Source note | uspto-grants-2011_12 |