HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde, 3-(2-hydroxyethoxy)- → 2-(3-((3-(Isoquinolin-5-ylamino)pyrrolidin-1-yl)methyl)phenoxy)ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde, 3-(2-hydroxyethoxy)- | HCID 6453965 | — |
| Reactant | N-(Pyrrolidin-3-yl)isoquinolin-5-amine | HCID 57936477 | — |
| Product | 2-(3-((3-(Isoquinolin-5-ylamino)pyrrolidin-1-yl)methyl)phenoxy)ethanol | HCID 25008327 | — |
Reaction Steps
Reaction of N-(pyrrolidin-3-yl)isoquinolin-5-amine with 3-(2-hydroxyethoxy)benzaldehyde using the method of Example 8 afforded the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071779B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-e69c79c057754bb595f005216ee6a5d2 |
| Source note | uspto-grants-2011_12 |