反应详情

To a stirred suspension of 4-[(4,5-dihydro-2-thiazolyl)amino]tetrahydro-3,5-bis(phenylmethylene)-2H-pyran-4-ol (2.5 g, 6.6 mmole) in toluene (100 ml) is added slowly a solution of titanium tetrachloride (0.63 g, 3.3 mmole) in toluene (6.1 ml). The yellow mixture is heated at reflux temperature for 45 minutes.

1. temperatureThe yellow mixture is heated
2. temperatureat reflux temperature for 45 minutes