Sulfuric Acid → 1-(2-Ethyl-butyl)-cyclohexanecarboxylic acid

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of 1-(2-Ethyl-butyl)-cyclohexanecarboxylic acid t-butyl ester (2.0 g, 7.45 mmol) in AcOH (6 mL) 4M H2SO4 (0.6 mL, 2.4 mmol) was added dropwise at 95° C. After 18 h at this temperature, another portion of AcOH (4 mL) and 4M H2SO4 (0.6 mL, 2.4 mmol) was added and stirring at 95° C. was continued for 4 h. Then the reaction was complete according to GC. The reaction mixture was concentrated and then worked up by extraction to afford 1.4 g (88%) 1-(2-ethyl-butyl)-cyclohexanecarboxylic acid, purity 99% (GC area).

Provenance & Evidence