HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Diethyl-3-nitroaniline → HCID 59800734, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Diethyl-3-nitroaniline | HCID 14146107 | — |
| Reactant | HCID 59800732 | HCID 59800732 | — |
| Product | HCID 59800734 | HCID 59800734 | 48% |
Reaction Steps
292 μl (2.085 mmol; 5 eq.) of (S)-4-chlora-alpha-methylbenzylamine (3) react according to GP-1B with 76 mg (0.417 mmol; 1.0 eq.) of 2-hydroxymethyl-4-methoxybenzyl-boronic acid (2). Flash chromatographical purification (hexane/ethylacetate 10:1) yields 58.6 mg (0.2 mmol; 48%) of the desired amine 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071810B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-43895db5158c406585e0e14c54c90937 |
| Source note | uspto-grants-2011_12 |