1-Methylimidazole → HCID 86626126, compound

Participants

Reaction Steps

Into a 500 mL round-bottomed flask equipped with a stir bar, Argon inlet and addition funnel was dissolved 1-methylimidazole (25 g, 0.31 mol) in trichloroethylene (100 mL). With stirring chloromethyl methyl ether (35 g, 0.43 mol) was added slowly dropwise over a 0.5 h period. The mixture warmed and a turbid, two-layer mixture formed upon addition. The mixture was refluxed 2 h, cooled and poured into a separatory funnel. The organic layer was separated, filtered and the solvent was removed under vacuum at 45° C. to yield a tan-beige viscous liquid (52 g).

Provenance & Evidence