HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 656749Generated: October 29, 2026
4-(5-Ethoxycarbonylmethyl-2-methoxy-phenoxy)-3-isopropylsulfanylmethyl-benzoic acid methyl ester → 4-(5-Ethoxycarbonylmethyl-2-methoxy-phenoxy)-3-isopropylsulfanylmethyl-benzoic acid
https://huagongshe.com/reaction/656749
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-(5-Ethoxycarbonylmethyl-2-methoxy-phenoxy)-3-isopropylsulfanylmethyl-benzoic acid methyl ester | HCID 58372842 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-(5-Ethoxycarbonylmethyl-2-methoxy-phenoxy)-3-isopropylsulfanylmethyl-benzoic acid | HCID 58372713 | — |
Reaction Steps
4-(5-Ethoxycarbonylmethyl-2-methoxy-phenoxy)-3-isopropylsulfanylmethyl-benzoic acid methyl ester (0.5 g, 1.16 mmol) and sodium methylthiolate (0.16 g, 2.3 mmol) were combined in DMF (20 mL) and stirred at 65° C. for 1 hour. After an acidic work-up, the crude material was purified by preparative HPLC to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08071807B2 |
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| Source dataset | uspto-grants-2011_12 |
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| ORD ID | ord-b52589ef02f8470bbf57ad3749845091 |
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| Source note | uspto-grants-2011_12 |
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