HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (3-Benzyloxy-4-chloro-phenyl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | (3-Benzyloxy-4-chloro-phenyl)-acetic acid | HCID 58149177 | — |
| Product | (3-Benzyloxy-4-chloro-phenyl)-acetic acid ethyl ester | HCID 58847546 | — |
Reaction Steps
(3-Benzyloxy-4-chloro-phenyl)-acetic acid (8 g) was treated with hydrogen chloride (4N in 1,4-dioxane; 6 mL) in EtOH (100 mL) at 80° C. for 3 hours. After concentrating to dryness, the residue was purified by silica gel chromatography to give (3-benzyloxy-4-chloro-phenyl)-acetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071807B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-f70ffef58eda44899ee36c9aeb402d1c |
| Source note | uspto-grants-2011_12 |