HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 5,6-Dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 5,6-Dihydro-5-oxo-pyrazolo(1,5-c)quinazoline-2-carboxylic acid | HCID 135496819 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 5,6-Dihydro-5-oxopyrazolo[1,5-c]quinazoline-2-carbonyl chloride | HCID 135735624 | — |
Reaction Steps
4.8 g (0.019 mole) of 5,6-dihydro-5-oxopyrazolo[1,5-c]-quinazoline-2-carboxylic acid, sodium salt is added to a solution of 3.27 g (0.026 mole) of oxalyl chloride in 200 ml of benzene. The suspension is stirred at room temperature for 20 minutes and then refluxed under nitrogen for 2 hours. The solvent is stripped to give the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04128644 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-8a0bc70692284a48adc2b15eb0e2944e |
| Source note | uspto-grants-1978_12 |