反应详情

A solution of 1,1-dimethylethyl [1-(2-{[6-(methyloxy)-3-nitro-2-pyridinyl]amino}ethyl)-4-piperidinyl]carbamate (3.0 g, 7.6 mmol) in ethanol (500 ml) was hydrogenated for 2 hours over 10% palladium on charcoal (50% dispersion with water, 1.5 g). The mixture was filtered, evaporated, and azeotroped with chloroform to afford a purple oil (2.8 g, 100%).

1. filtrationThe mixture was filtered
2. customevaporated
3. customazeotroped with chloroform