HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dihydrofuro[2,3-c]pyridin-5-ylmethanol → 2,3-Dihydrofuro[2,3-c]pyridine-5-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dihydrofuro[2,3-c]pyridin-5-ylmethanol | HCID 57423121 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2,3-Dihydrofuro[2,3-c]pyridine-5-carbaldehyde | HCID 57423116 | 70% |
Reaction Steps
2,3-Dihydrofuro[2,3-c]pyridin-5-ylmethanol (1.31 g, 8.7 mmol) was dissolved in DCM (100 ml), treated with manganese (IV) dioxide (6 g, 69 mmol) and heated under reflux for 18 h. Filtration through kieselguhr and evaporation of the filtrate to dryness gave an oil (0.9 g, 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071592B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-204f64b952994cb287df8dd77a7e986a |
| Source note | uspto-grants-2011_12 |