HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86635341, compound → HCID 68994150, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86635341 | HCID 86635341 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68994150 | HCID 68994150 | 96% |
Reaction Steps
A solution of phenylmethyl ({(3R,4R)-1-[2-(7-fluoro-2-oxo-1(2H)-quinolinyl)ethyl]-4-hydroxy-3-pyrrolidinyl}methyl)carbamate (0.3 g) in dry methanol (15 mL) was treated with 10% Pd/C (0.08 g) and shaken under 15 psi at room temperature for 2 hours. The Pd catalyst was filtered through Celite®. The filtrate was evaporated to dryness to give an oil (0.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071592B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-87d42e190cb34e3396cde5bfceb992b6 |
| Source note | uspto-grants-2011_12 |