反应详情

To a solution of phenylmethyl ({(3S)-1-[2-(7-fluoro-2-oxo-1(2H)-quinolinyl)ethyl]-3-pyrrolidinyl}methyl)carbamate (820 mg, 1.94 mmol) in MeOH (30 mL) was added 5% palladium on carbon (200 mg, 50% by weight with water). The mixture was hydrogenated at 15 psi for 2.5 h, filtered through a pad of Celite®, and concentrated to give a clear oil which darkened and solidified on standing (555 mg, 99%).

1. filtrationfiltered through a pad of Celite®
2. concentrationconcentrated
3. customto give a clear oil which