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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 657067Generated: October 30, 2026

HCID 86635347, compound → HCID 68995687, compound

https://huagongshe.com/reaction/657067

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86635347HCID 86635347—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 68995687HCID 68995687107%

Reaction Steps

To a solution of phenylmethyl [((3S)-1-{2-[7-(methyloxy)-2-oxo-1,5-naphthyridin-1(2H)-yl]ethyl}-3-piperidinyl)methyl]carbamate (0.21 g, 0.44 mmol) in MeOH (30 mL) was added 10% Palladium on carbon (0.20 g) and the solution subjected to H2 at 50 PSI on a Parr shaker. The solution was filtered through a pad of Celite® and concentrated under reduced pressure to give desired product (0.149 g, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08071592B2
Source datasetuspto-grants-2011_12
ORD IDord-027e73bcce7042b885f8576100d03a90
Source noteuspto-grants-2011_12