HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86635347, compound → HCID 68995687, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86635347 | HCID 86635347 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68995687 | HCID 68995687 | 107% |
Reaction Steps
To a solution of phenylmethyl [((3S)-1-{2-[7-(methyloxy)-2-oxo-1,5-naphthyridin-1(2H)-yl]ethyl}-3-piperidinyl)methyl]carbamate (0.21 g, 0.44 mmol) in MeOH (30 mL) was added 10% Palladium on carbon (0.20 g) and the solution subjected to H2 at 50 PSI on a Parr shaker. The solution was filtered through a pad of Celite® and concentrated under reduced pressure to give desired product (0.149 g, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071592B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-027e73bcce7042b885f8576100d03a90 |
| Source note | uspto-grants-2011_12 |