HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[2,2-bis(methyloxy)ethyl]-6-(methyloxy)-3-nitro-2-pyridinamine → N2-[2,2-Bis(methyloxy)ethyl]-6-(methyloxy)-2,3-pyridinediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[2,2-bis(methyloxy)ethyl]-6-(methyloxy)-3-nitro-2-pyridinamine | HCID 68812011 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N2-[2,2-Bis(methyloxy)ethyl]-6-(methyloxy)-2,3-pyridinediamine | HCID 86635355 | — |
Reaction Steps
A solution of N-[2,2-bis(methyloxy)ethyl]-6-(methyloxy)-3-nitro-2-pyridinamine (2.5 g, 10 mmol) in methanol was hydrogenated at 50 psi for 0.5 h over 10% palladium on charcoal (0.9 g). The mixture was filtered, evaporated, and azeotroped with chloroform affording a dark oil (2.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08071592B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-646ff2d3a8844fb6b61618b09c994005 |
| Source note | uspto-grants-2011_12 |