Methanol → HCID 68809804, compound

Participants

Reaction Steps

To a solution of 4-{2-[(3S,4R)-3-(aminomethyl)-4-hydroxy-1-piperidinyl]ethyl}-6-(methyloxy)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one (170 mg; 0.508 mmol) in DCM:MeOH: 10:1 was added MnO2 (156 mg; 1.52 mmol). The reaction mixture was stirred at ambient temperature under N2 for 2 days, filtered, and concentrated to obtain the product (142 mg; 84%).

Provenance & Evidence