HCID 86635370, compound → HCID 68991981, compound

Participants

Reaction Steps

A solution of phenylmethyl ({(3R,4S)-1-[2-(7-fluoro-2-oxo-1(2H)-quinolinyl)ethyl]-4-hydroxy-3-piperidinyl}methyl)carbamate (525 mg; 1.16 mmol) in EtOH (100 mL) was added 20% Pd(OH)2/C (100 mg). The mixture was hydrogenated at 1 atm of H2 at ambient temperature for 2 h. The crude product was filtered through Celite, washed with ethanol and concentrated under reduced pressure to obtain the product as a pale yellow oil (356 mg; 96%).

Provenance & Evidence